Friday, September 3, 2010

Amyloidosis Spleen

July 9, 2009 by Admin  
Filed under Pathology

Amyloidosis Spleen may have 2 patterns

  • LARDACEOUS SPLEEN: associated primarily with deposition in the stroma of the Red pulp and
  • SAGO SPLEEN: associated with deposition in the stroma of White pulp

Spleen may be normal sized or moderate to markedly enlarged.

The Cut surface shows one of the 2 patterns;

lardaceous spleenLardaceous spleen : The slice of spleen is identified by its dark colour and presence of notches (1). it is characterised by diffuse map -like areas of pale ,waxy translucency.

sago spleen or

Sago spleen The slice of spleen is identified by its dark colour and presence of notches (1). The sectioned surface shows presence of pale waxy translucency seen around the gray central arterioles (2) forming nodular pattern , it is seen as multiple pale foci corresponding to the regions of splenic follicles.

SPECIAL STAINS  of AMYLOIDOSIS:

  • STAIN ON GROSS:Lugol’s Iodine
  • H & E Staining
  • Metachromatic Stains( Rosaniline Dyes)
  • Congo Red & Polarised Light
  • Fluorescent Stains:thioflavin-T
  • Immunohistochemistry

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Related posts:

  1. Amyloidosis Liver
  2. MILIARY TUBERCULOSIS SPLEEN
  3. Amyloidosis Kidney
  4. CVC SPLEEN
  5. PALE INFARCT SPLEEN

Comments

3 Responses to “Amyloidosis Spleen”
  1. Dirnov says:

    medicaldude.com to GoogleReader!
    Have a nice day

  2. Any information on your sources though?

  3. Admin says:

    We are the a Team of 4 Mbbs/MS Doctors , and sources of information is mainly different books from our library or sometimes from internet .

    Thanks

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